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Is it time to help the liver do its job and perform well for you? Toxic wastes can accumulate in the colon and liver, and then can circulate throughout the body via the bloodstream. Some symptoms of this condition can include depression, irritability, fatigue, gastrointestinal irregularities, acid indigestion and allergies. The liver controls the thyroid, makes the bile stored in the gallbladder and works with the pancreas. The liver stores excess fat leading to a fatty liver. Helps with lymphatic system, and kidney function.